报告时间：2019年4月8日（星期一）下午14:00

报告地点：生物楼406会议室

报告人：雷群英教授，复旦大学

　　报告摘要：

　　Metabolites and related proteins are essential for cell physical and pathological functions. Cells sense specific metabolites to coordinate biological processes in response to metabolic fluctuations. Metabolic reprogramming is one of the critical features in cancer. Tumor cells preferentially utilize glycolysis instead of oxidative phosphorylation in the presence of oxygen, namely ‘Warburg Effect’. With the comprehensive studies in this field, Warburg Effect is beyond glycolysis. Many different metabolic pathways are added into this picture, providing further evidence for the critical role of metabolism in tumorigenesis and cancer development. My laboratory mainly focuses on metabolic stress and tumorigenesis. Of particular interest, I plan to share our recent progress on non-canonical enzyme function of LDHA.

　　报告人简介：

　　雷群英，教授，博士生导师，长江特聘教授，研究方向为肿瘤代谢。2002年获上海医科大学博士学位，之后在美国加州大学洛杉矶分校做博士后研究，2006年加入复旦大学，研究成果以通讯作者/共同通讯作者在Cancer Cell、Cell Metabolism、Molecular Cell、J.Clin.Invest 和Nature Communi. 等杂志。获得科技部重大项目和基金委重大、杰出青年基金等项目资助。目前担任中国细胞生物学协会细胞代谢分会主委，全国医学生物化学与分子生物学协会副理事长和上海市生物化学与分子生物学协会副理事长兼秘书长。

　　联系人：1809组 叶明亮

　　联系电话：84379610