报告时间：2012年10月11日（星期四）上午 8:30

报告地点：催化楼一楼会议室

报告人：Pierre H. Dixneuf

Centre of Catalysis and Green Chemistry, Institut sciences chimiques,

UMR-6226 CNRS-Université de Rennes, Campus de Beaulieu, 35042 Rennes Cedex, France

报告人简介：

Research topics

- Carbon-rich organometallics in new molecular architectures

Chemistry of modele moieties for catalysis: carbenes, vinylidenes, allenylidenes, cumulenes, Carbynes

- Homogeneous catalysis

. Functional carbonates, oxazolidinones in organic synthesis, heterocycles via catalysis:

. vinylidenes in catalysis

. selective formation of C-C bonds

. alkene metathesis

Design of catalysts, and catalysis for fine chemicals production

？ 340 papers in international journals including, 11 review articlesand 11 book chapters

？ 5 patents, abook “ruthenium catalysts in fine chemistry” Springer, june 04

Recent Key events and positions

2000 Initiator and first Director de l'Institut de Chimie de Rennes CNRS-university

2000 Member of the ？ Institut universitaire de France ？ since 2000

2001 Elected vice president for research of the university of Rennes jan 2001-Dec 2004

2002 Launch of the international master in chemistry in English at the university of Rennes

2004 publication of the book “ruthenium catalysts in fine chemistry” following 320 international publications

Awards and Distinctions

1990　　  A. von Humboldt prize for Research

1994　　  Académie des Sciences award

1996 　　　　 Doctor Honoris Causa, Waterloo, Canada

2000 　　 Prix Le Bel French Chemical Society

2000　　　　　 Member of the ？ Institut universitaire de France ？

2001　　 Grignard-Wittig Prize (GDCh)

2006 　　 Sacconi medal

2006　　  Grand prix IFP académie des sciences

Journal Advisory, Editorial boards

1995　  　Chemical communications (95→04) 　　　　　　　　　　　　　

1998 　　 New journal of chemistry (98 →)

1997 　　 “Topics in Organometallic Chemistry” series, Springer

2000 　　　　 Advances in Synthesis and catalysis

报告摘要：

The catalytic functionalization of inert sp2 C-H bonds for selective C-C bond cross-couplings has a tremendous importance for molecules and materials synthesis. It has the potential replace, with better atom and energy economy, the very useful catalytic cross-coupling reactions between an organometallic (M = Li, MgX, ZnX, BR2, SnR3,…) and an organic halide, when regioselectivity is found.

Our objective is to present the advantages brought by cheap, air and water stable ruthenium(II) catalysts for cross-coupling reactions of various inert C-H bonds, with C-X or another C-H bond, and to show that operating in water as solvent favours the process.
- The regioselective syntheses of polyheterocycles and tridentate ligands will be shown, using ruthenium(II)-carboxylate and carbonate systems, and the mechanism of C-H bond activation/deprotonation will be discussed.

- The direct functionalization of imines as a route to functional ketones and bulky amines via sequential C-H bond arylation/hydrosilylation will be presented.

- The dehydrogenative oxidative cross-coupling reactions involving two different sp2C-H bonds will be demonstrated in alkenylation reactions of arenes directed by heterocycle with ruthenium catalysts and oxidizing partners.

- Catalysis in water : Examples of C-H bond functionalization in water will be selected.

报告联系人：203组 余正坤（9227）